本書圍繞基因組學及應用為主要內容進行編寫,著重介紹高通量測序技術在現(xiàn)代生命科學中的應用、大數(shù)據(jù)時代的數(shù)據(jù)產生和存貯及應用進展、個人基因組計劃及個性化醫(yī)療等主題,精選來自Nature、Science等生物醫(yī)藥、農業(yè)等方面頂級期刊中有關基因組及其應用的文獻,解釋文中的生詞熱詞,解析疑難句,設置課后習題,增設閱讀材料,幫助在校高年級大學生以及研究生學習、了解基因組及其在生命科學各領域的進展及其應用,并掌握基因組相關專業(yè)英語的基本術語和表達方式,切實提高讀者的實際運用專業(yè)英語的能力。
基因組學在生命科學各個領域中發(fā)揮著越來越重要的作用,本書精選來自Nature、Science等生物醫(yī)藥、農業(yè)等方面**期刊中有關基因組及其應用的文獻,著重介紹高通量測序技術在現(xiàn)代生命科學中的應用、大數(shù)據(jù)時代的數(shù)據(jù)產生和存貯及應用進展、個人基因組計劃及個性化醫(yī)療等主題。
孫穎,女,華大基因研究院副研究員。中山大學博士學歷,美國約翰霍普金斯大學科學教育學碩士。有15年從事國內外教學、科研等經歷,有美國三年以上相關英語教學(全英文講授生物學,物理和化學等課程)工作經驗,具備先進的教育教學理念,對中西方教學體系、教育模式和國際化教學有深刻理解。
Chapter 1 Next generation Sequencing (NGS)
Lesson 1 From Convention to Second generation Sequencing
Lesson 2 Application of Next generation Sequencing
Lesson 3 First Baby Born after Full Genetic Screening of Embryos
Chapter 2 Big Data
Lesson 1 Too Much Information: Better Health from Big Data
Lesson 2 Life Sciences in Big Data Era
Lesson 3 Big Data Meets Public Health
Chapter 3 Personal Genomics & Personalized Medicine
Lesson 1 The Advent of Personal Genome Sequencing
Lesson 2 The Future of Personal Genomics
Lesson 3 Obstacles to the Translation of Personalized Medicine into the Clinic
Chapter 4 Animal & Plant Genome Research and Its Agricultural Applications
Lesson 1 Plant and Animal Sequencing
Lesson 2 Animal Code: Our Favorite Genomes
Lesson 3 Sequencing of Animal/Plant Genomes and Its Application
Chapter 5 Metagenomics
Lesson 1 Metagenomics: The Science of Biological Diversity
Lesson 2 How Gut Bacteria Help Make Us Fat and Thin
Lesson 3 Next generation Sequencing Propels Environmental Genomics to the Front Line of Research
Chapter 6 Genomes and Biodiversity
Lesson 1 Genome 10K: a Proposal to Obtain Whole Genome Sequence for 10000
Vertebrate Species
Lesson 2 Biodiversity,Genomes,and DNA Sequence Databases
Lesson 3 Examples of Genome & Transcriptome Projects
Chapter 7 Biobanking
Lesson 1 Current Status,Challenges,Policies & Bioethics of Biobanks
Lesson 2 Building Better Biobank
Lesson 3 Biobank Promises to Pinpoint the Cause of Disease
Chapter 8 Big Resources in Biobanks
Lesson 1 Specimen Types for DNA Net Earth
Lesson 2 Specimen Collections in U.S. Biobanks: Results from a National Survey
Lesson 3 Examples of Aquatic Biobanks Worldwide
Glossary
References