Contributors

Preface

SECTION I

THE IMMUNE SYSTEM IN HEALTH AND

DISEASE

1. Approach to the Patient with anInfectious Disease

2. Molecular Mechanisms of MicrobialPathogenesis

3. The Human Microbiome

4. Genomics and Infectious Disease

5. Immunization Principles and Vaccine Use

6. Health Recommendations for International Travel

7. Laboratory Diagnosis of Infectious Diseases

8. Climate Change and Infectious Disease

9. Infections in Veterans Returning fromForeign Wars

10. Microbial Bioterrorism

SECTION II

FEVER AND APPROACH TOTHE FEBRILEPATIENT

11. Fever

12. Fever and Rash

13. Fever of Unknown Origin

14. Atlas of Rashes Associated with Fever

15. Infections in Patients with Cancer

16. Infections in Transplant Recipients

17. Infections Acquired in HealthCare Facilities

18. Approach to the Acutely IllInfected Febrile Patient

19. Severe Sepsis and Septic Shock

SECTION III

INFECTIONS IN ORGAN SYSTE MS

20. Sore Throat, Earache, and Upper Respiratory Symptoms

21. Pneumonia

22. Lung Abscess

23. Bronchiectasis

24. Infective Endocarditis

25. Pericardial Disease

26. Infections of the Skin,Muscles, and Soft Tissues

27. Infectious Arthritis

28. Osteomyelitis

29. Intraabdominal Infectionsand Abscesses

30. Acute Infectious Diarrheal Diseasesand Bacterial Food Poisoning

31. Clostridium difficile Infection,Including Pseudomembranous Colitis

32. Acute Appendicitis and Peritonitis

33. Urinary Tract Infections,Pyelonephritis, and Prostatitis

34. Dysuria, Bladder Pain, and the InterstitialCystitis/Bladder Pain Syndrome

35. Sexually Transmitted Infections:Overview and Clinical Approach

36. Meningitis, Encephalitis, BrainAbscess, and Empyema

37. Chronic and Recurrent Meningitis

38. Chronic Fatigue Syndrome

39. Infectious Complicationsof Burns

40. Infectious Complicationsof Bites

SECTION IV

BACTERIAL INFECTIONS

41. Treatment and Prophylaxis ofBacterial Infections

42. Pneumococcal Infections

43. Staphylococcal Infections

44. Streptococcal Infections

45. Enterococcal Infections

46. Acute Rheumatic Fever

47. Diphtheria and OtherCorynebacterial Infections

48. Listeria monocytogenes Infections

49. Tetanus

50. Botulism

51. Gas Gangrene and Other ClostridialInfections

52. Meningococcal Infections

53. Gonococcal Infections

54. Haemophilus and Moraxella Infections

55. Infections Due to the HACEK Group andMiscellaneous Gram-Negative Bacteria

56. Legionella Infections

57. Pertussis and Other Bordetella Infections

58. Diseases Caused by Gram-NegativeEnteric Bacilli

59. Acinetobacter Infections

60. Helicobacter pylori Infections

61. Infections Due to Pseudomonas Speciesand Related Organisms

62. Salmonellosis

63. Shigellosis

64. Infections Due to Campylobacter and RelatedOrganisms

65. Cholera and Other Vibrioses

66. Brucellosis

67. Tularemia

68. Plague and Other Yersinia Infections

69. Bartonella Infections, IncludingCat-Scratch Disease

70. Donovanosis

71. Nocardiosis

72. Actinomycosis and Whipples Disease

73. Infections Due to MixedAnaerobic Organisms

74. Tuberculosis

75. Leprosy

76. Nontuberculous Mycobacterial Infections

77. Antimycobacterial Agents

78. Syphilis

79. Endemic Treponematoses

80. Leptospirosis

81. Relapsing Fever

82. Lyme Borreliosis

83. Rickettsial Diseases

84. Infections Due to Mycoplasmas

85. Chlamydial Infections

SECTION V

VIRAL INFECTIONS

86. Medical Virology

87. Antiviral Chemotherapy,

Excluding Antiretroviral Drugs

88. Herpes Simplex Virus Infections

89. Varicella-Zoster Virus Infections

90. Epstein-Barr Virus Infections,Including Infectious Mononucleosis

91. Cytomegalovirus and HumanHerpesvirus Types 6, 7, and 8

92. Molluscum Contagiosum, Monkeypox,and Other Poxvirus Infections

93. Parvovirus Infections

94. Human Papillomavirus Infections

95. Common Viral Respiratory Infections

96. Influenza

97. Human Immunodeficiency VirusDisease: AIDS and Related Disorders

98. Viral Gastroenteritis

99. Acute Viral Hepatitis

100. Chronic Hepatitis

101. Enterovirus, Parechovirus, andReovirus Infections

102. Measles (Rubeola)

103. Rubella (German Measles)

104. Mumps

105. Rabies and Other Rhabdovirus Infections

106. Arthropod-Borne and Rodent-BorneVirus Infections

107. Ebolavirus and Marburgvirus Infections

108. Zika Virus Infection and Zika-AssociatedCongenital Abnormalities

SECTION VI

PRION DISEASES

109. Prion Diseases

SECTION VII

FUNGAL INFECTIONS

110. Diagnosis and Treatment ofFungal Infections

111. Histoplasmosis

112. Coccidioidomycosis

113. Blastomycosis

114. Cryptococcosis

115. Candidiasis

116. Aspergillosis

117. Mucormycosis

118. Superficial Mycoses and Less CommonSystemic Mycoses

119. Pneumocystis Infections

SECTION VIII

PROTOZOAL AND HELMINTHICINFECTIONS

120. Laboratory Diagnosis of ParasiticInfections

121. Agents Used to Treat Parasitic Infections

122. Amebiasis and Infection withFree-Living Amebas

123. Malaria

124. Babesiosis

125. Atlas of Blood Smears of Malariaand Babesiosis

126. Leishmaniasis

127. Chagas Disease and AfricanTrypanosomiasis

128. Toxoplasma Infections

129. Protozoal Intestinal Infectionsand Trichomoniasis

130. Introduction to Helminthic Infections

131. Trichinellosis and Other TissueNematode Infections

132. Intestinal Nematode Infections

133. Filarial and Related Infections

134. Schistosomiasis and OtherTrematode Infections

135. Cestode Infections

SECTION IX

ENVENOMATIONS, INFESTATIONS, BITES,AND STINGS

136. Disorders Caused by Venomous Snakebites andMarine Animal Exposures

137. Ectoparasite Infestations andArthropod Injuries

Appendix

Laboratory Values of Clinical Importance

Review and Self-Assessment

Index