Thisbookiscomposedoftwenty-onechaptersthatcanbefurtherdividedintofourparts:(i)Abriefintroductiontopathophysiologyandthedisease.(ii)Thecellularandmolecularpathophysiologyincludingderegulationofsignaltransductionandmechanismsunderlyingaberrantcellproliferation,differentiationanddeath.(iii)Thefundamentalpathologicalprocessesthatcanappearindifferentdiseases,includingfluidandelectrolyteimbalance,acidandbasedisturbance,glucosemetabolismdisorder,lipidmetabolismdisorders,stress,fever,edema,ischemiaandreperfusion,shock,multi-organicdysfunction,andhypoxia.Knowledgeofthesebasicpathophysiologicalprocesseisessentialforunderstandingthegeneralmechanismsunderlyingmostofthediseases.(iv)Theorgandysfunctionsincludingheart,lung,liver,kidneyandthebrain.Thefocusinhislastpartisstillonthepathologicalprocessesandthemechanismsunderlyingtheorganinsufficiencyorfailure.Eachchapterisorganizedbythesegmentsemphasizingrespectivelythegeneralconcepts,theetiologyandpathogenesis,thealterationsofmetabolismandthefunction,andaswellastheprinciplesforthepreventionandtherapies,whicharealsothekeyforteachingandlearninginpathophysiologycourses.Theclinicaldoctorscanchoosethebookasarefresherandupdatetheirunderstandingthemechanismsofdiseases.Nursesandotherpractitionerswillfindthattheconciseformatandbroad/newscopeofthebookfacilitatetheirunderstandingofbasicdiseaseentities.《BR》

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